Predictors associated with augmented Left ventricular systolic function after pulmonary valve replacement
Tetralogy of Fallot (TOF) has been more than five decades since the first total TOF repair was performed in 1955. TOF accounts for almost 10% of all cases of congenital heart disease and is one of the main common cyanotic congenital heart disorder. Reparative surgery grants more than 85% of children born with TOF to continue into adulthood. Through the development of surgical procedures, perioperative encourage, and imaging modalities, long-term results have also considerably progressed in the previous 2 decades, but resultant anomalies such as significant right ventricular (RV) enlargement, dyskinetic severe pulmonary regurgitation (PR), interventricular septal motion, and reduced RV systolic functioning are still there in more than half of these patients. It is now commonly acknowledged that pulmonary valve replacement (PVR) in patients with severe PR and concomitant RV volume overload can consequence in the preservation or recovery of RV function.
As such, much of the present literature on congenital heart disorder centers on the preservation
and recovery of RV function in patients with repaired TOF (rTOF
). Although LV volume and systolic function can fluctuate
in adults at the late stage after TOF repair, PVR may have other benefits on LV systolic function. Researchers found that the only independent CMR indicator of postoperative improvement in LV systolic function is preoperative LV systolic dysfunction. This may be auxiliary to normalization of interventricular interactions after PVR, but the exact mechanisms responsible are not known yet. Other study is
needed to further analyze the findings and determines accurate predictors associated with augmented LVEF following PVR.
Tetralogy of Fallot (TOF) has been more than five decades since the first total TOF repair was performed in 1955. TOF accounts for almost 10% of all cases of congenital heart disease and is one of the main common cyanotic congenital heart disorder. Reparative surgery grants more than 85% of children born with TOF to continue into adulthood. Through the development of surgical procedures, perioperative encourage, and imaging modalities, long-term results have also considerably progressed in the previous 2 decades, but resultant anomalies such as significant right ventricular (RV) enlargement, dyskinetic severe pulmonary regurgitation (PR), interventricular septal motion, and reduced RV systolic functioning are still there in more than half of these patients. It is now commonly acknowledged that pulmonary valve replacement (PVR) in patients with severe PR and concomitant RV volume overload can consequence in the preservation or recovery of RV function.
As such, much of the present literature on congenital heart disorder centers on the preservation and recovery of RV function in patients with repaired TOF (rTOF). Although LV volume and systolic function can fluctuate in adults at the late stage after TOF repair, PVR may have other benefits on LV systolic function. Researchers found that the only independent CMR indicator of postoperative improvement in LV systolic function is preoperative LV systolic dysfunction. This may be auxiliary to normalization of interventricular interactions after PVR, but the exact mechanisms responsible are not known yet. Other study is needed to further analyze the findings and determines accurate predictors associated with augmented LVEF following PVR.
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